2007 Mercedes-Benz E350 power train problems
21 owner complaints filed with NHTSA name the power train on the 2007 Mercedes-Benz E350 — 6% of all complaints for this model year.
What owners report
“The contact owns a 2007 Mercedes-Benz E350. The contact stated while driving approximately 65 MPH, the check engine warning light illuminated and with an abnormal sound coming from the gear shifter. The contact stated there was a failure with the transmission and the vehicle would not exceed 65…”
filed Jun 27, 2022
“At about 87,000 miles, the car is essentially useless because of a known defect. The balance shaft, engine intake manifold and transmission conductor plate need to be replaced. Mercedes will not take responsibility even though there was a class action lawsuit.”
filed Mar 25, 2019
Verbatim excerpts from complaints filed with NHTSA. Reports are not independently verified.
Related service bulletins
Single throttle lift-off clunking noise from the side shaft when moving off (audible at the outboard end). The noise is heard once in each instance when changing direction of travel. Note: Sound file in attachment Cause…
LI35.30-P-058566 · Service Bulletin/Repair Instructions · issued Jul 14, 2026Complaint Single throttle lift-off clunking noise from the side shaft when moving off (audible at the outboard end). The clunk is heard once when changing from forward to reverse (and vice versa). Note: Sound file in…
LI33.30-P-056665 · Service Bulletin/Repair Instructions · issued Nov 15, 2025
Power Train problems in other E350 years
| Year | Reports | Share |
|---|---|---|
| 2016 E350 | 5 | 10% |
| 2015 E350 | 1 | 3% |
| 2014 E350 | 15 | 5% |
| 2013 E350 | 7 | 4% |
| 2012 E350 | 10 | 5% |
| 2011 E350 | 6 | 3% |
| 2010 E350 | 14 | 8% |
| 2009 E350 | 2 | 3% |
| 2008 E350 | 5 | 3% |
| 2006 E350 | 37 | 9% |
Other reported problem areas on the 2007 Mercedes-Benz E350
Counts are unique NHTSA complaints naming this component group. Complaints are unverified owner reports; mileage is computed only from complaints that included a usable odometer reading.