2010 Mercedes-Benz E350 engine problems
15 owner complaints filed with NHTSA name the engine on the 2010 Mercedes-Benz E350 — 8% of all complaints for this model year.
What owners report
“fast acceleration then slow down goes into limp mode . happens when passing a car or taking off fast like entering into traffic . very dangerous. will be calling mercedes benz tomorrow. bought car used approximately 4 months ago. thanks”
filed Jul 24, 2025
“Smell gasoline on driver side. Can’t fill tank up or the smell is unbearable. Gas consumption is high. Engine light is on , suspension make a lot of noise, and ticking on driver side.”
filed Apr 14, 2025
Verbatim excerpts from complaints filed with NHTSA. Reports are not independently verified.
Related recalls
- Various control units may have been updated with incorrect software configuration during…Campaign 22V168000 · Mar 18, 2022
Engine problems in other E350 years
| Year | Reports | Share |
|---|---|---|
| 2016 E350 | 5 | 10% |
| 2015 E350 | 2 | 6% |
| 2014 E350 | 20 | 7% |
| 2013 E350 | 15 | 9% |
| 2012 E350 | 20 | 9% |
| 2011 E350 | 13 | 6% |
| 2009 E350 | 5 | 8% |
| 2008 E350 | 13 | 8% |
| 2007 E350 | 28 | 8% |
| 2006 E350 | 50 | 13% |
Other reported problem areas on the 2010 Mercedes-Benz E350
Counts are unique NHTSA complaints naming this component group. Complaints are unverified owner reports; mileage is computed only from complaints that included a usable odometer reading.