2010 Mercedes-Benz E350 structure problems
11 owner complaints filed with NHTSA name the structure on the 2010 Mercedes-Benz E350 — 6% of all complaints for this model year.
What owners report
“Car was found to have the rear subframe corrosion for issue. But also the brake lines were corroded very badly. They should be covered under the rear subframe extended warranty replacement. The rear brake lines are an frequent issue and almost always shows up when the subframe begins to rot. Also…”
filed Jan 19, 2026
“When braking the car pulls hard off the road. inspection showed rear subframe rusted and control arms are not attached securely to frame. Unsafe to drive”
filed Jan 1, 2025
Verbatim excerpts from complaints filed with NHTSA. Reports are not independently verified.
Related service bulletins
Complaint The underfloor paneling is loose or sags (picture 1). Cause Mounting clips broken or not correctly engaged. Remedy Replace all mounting clips with collar nuts with shims (picture 2): Adapter set (203 589 02 31…
LI61.25-P-047933 · Service Bulletin/Repair Instructions · issued Jun 2, 2026
Structure problems in other E350 years
| Year | Reports | Share |
|---|---|---|
| 2016 E350 | 7 | 14% |
| 2015 E350 | 4 | 13% |
| 2014 E350 | 24 | 9% |
| 2013 E350 | 18 | 11% |
| 2012 E350 | 8 | 4% |
| 2011 E350 | 15 | 7% |
| 2009 E350 | 3 | 5% |
| 2008 E350 | 6 | 3% |
| 2007 E350 | 2 | 1% |
| 2006 E350 | 5 | 1% |
Other reported problem areas on the 2010 Mercedes-Benz E350
Counts are unique NHTSA complaints naming this component group. Complaints are unverified owner reports; mileage is computed only from complaints that included a usable odometer reading.